Dexlansoprazole drug is a proton pump inhibitor (PPI) used to reduce stomach acid production. It is commonly prescribed to treat conditions like gastroesophageal reflux disease (GERD) and erosive esophagitis. The drug works by inhibiting the proton pumps in the stomach lining that produce acid, thereby reducing acid levels and alleviating symptoms associated with excess stomach acid.
Key Information about Dexlansoprazole drug
Uses
Gastroesophageal Reflux Disease (GERD): Reduces symptoms such as heartburn and regurgitation.
Erosive Esophagitis: Heals and maintains the healing of erosive esophagitis caused by stomach acid.
Maintenance Therapy: Prevents the recurrence of erosive esophagitis.
Mechanism of Action
Dexlansoprazole drug has a unique dual delayed-release formulation. This means it releases the medication in two phases at different times, providing a prolonged effect in reducing stomach acid production over a 24-hour period.
Dosage
The typical dosage for treating erosive esophagitis is 60 mg once daily for up to 8 weeks.
For maintaining healing and treating symptomatic non-erosive GERD, a common dose is 30 mg once daily.
Side Effects
Common side effects may include:
Headache
Diarrhea
Abdominal pain
Nausea
Rare but serious side effects can include:
Severe allergic reactions
Low magnesium levels
Bone fractures with long-term use
Precautions
Inform your doctor of any other medications you are taking to avoid potential interactions.
Use caution if you have a history of liver disease.
Prolonged use should be monitored by a healthcare provider due to potential risks such as vitamin B12 deficiency or bone fractures.
Manufacturers of dexlansoprazole drug
Dexlansoprazole is produced by several pharmaceutical companies. The main brand is Dexilant, which is manufactured by Takeda Pharmaceuticals. Another manufacturer providing generic versions is TWi Pharmaceuticals.
Further Information
For more detailed information on dexlansoprazole, you can visit the following websites:
Takeda Pharmaceuticals – Dexilant
These sources provide comprehensive details about the drug, including its uses, side effects, interactions, and patient information.
Dexlansoprazole is used primarily for the following medical conditions related to excess stomach acid:
1. Gastroesophageal Reflux Disease (GERD)
Purpose: To alleviate symptoms such as heartburn, regurgitation, and discomfort caused by acid reflux.
Mechanism: Reduces the amount of acid produced in the stomach, thereby decreasing the potential for acid to move back up into the esophagus.
2. Erosive Esophagitis
Purpose: To heal damage to the esophagus lining caused by stomach acid.
Usage: Typically used for a specific duration (up to 8 weeks) to treat the active inflammation and damage.
Maintenance: Often prescribed to maintain healing and prevent recurrence of esophagitis.
3. Symptomatic Non-Erosive GERD
Purpose: To manage symptoms such as heartburn in patients who do not have erosive esophagitis.
Usage: Used for relief of daytime and nighttime heartburn.
4. Long-term Maintenance Therapy
Purpose: To prevent the recurrence of erosive esophagitis.
Usage: Prescribed at a lower dose for long-term use after initial healing is achieved.
Mechanism of Action
Dexlansoprazole is a proton pump inhibitor (PPI) that works by blocking the proton pumps in the stomach lining, which are responsible for producing stomach acid. Its dual delayed-release formulation allows for a more extended period of acid suppression, providing effective control over acid production throughout the day and night.
Common Side Effects of dexlansoprazole drug
Headache
Diarrhea
Nausea
Abdominal pain
Serious Side Effects
Severe allergic reactions
Low magnesium levels
Increased risk of bone fractures with long-term use
Important Considerations
Drug Interactions: Inform your healthcare provider of all medications you are taking to avoid potential interactions.
Liver Disease: Use with caution if you have a history of liver disease.
Monitoring: Long-term use requires monitoring by a healthcare provider to prevent complications such as vitamin B12 deficiency or bone fractures.
For more detailed information on the uses and precautions of dexlansoprazole, you can visit resources such as Drugs.com – Dexlansoprazole and the Mayo Clinic.
How to Use Dexlansoprazole drug
Dosage and Administration
Follow Doctor’s Instructions: Always take dexlansoprazole exactly as prescribed by your healthcare provider.
Dosage Form:
Typically available in delayed-release capsules.
Frequency:
Erosive Esophagitis: 60 mg once daily for up to 8 weeks.
Maintenance of Healed Erosive Esophagitis and Relief of Heartburn: 30 mg once daily.
Symptomatic Non-Erosive GERD: 30 mg once daily for 4 weeks.
Timing:
Take the medication at the same time each day for consistency and maximum effectiveness.
It can be taken with or without food.
Administration:
Swallow the capsule whole with water.
Do not crush, chew, or split the capsule as it is designed to release the medication slowly.
For Those Who Have Difficulty Swallowing Capsules:
Open the capsule and sprinkle the contents on a spoonful of applesauce. Swallow immediately without chewing.
Missed Dose for dexlansoprazole drug
If you miss a dose, take it as soon as you remember.
If it is almost time for the next dose, skip the missed dose.
Do not take two doses at the same time to make up for a missed dose.
Precautions
Drug Interactions: Inform your healthcare provider about all the medications you are currently taking to avoid potential drug interactions.
Liver Disease: Use with caution if you have a history of liver disease.
Long-term Use:
Long-term use of dexlansoprazole drug should be monitored by a healthcare provider to prevent potential risks such as vitamin B12 deficiency, magnesium deficiency, and an increased risk of bone fractures.
Storage
Store at room temperature away from moisture and heat.
Additional Information about dexlansoprazole drug
For more detailed information on how to use dexlansoprazole, you can refer to trusted medical resources:
Takeda Pharmaceuticals – Dexilant
These resources provide comprehensive details regarding the medication, including indications, usage instructions, side effects, and precautions.
The side effects of dexlansoprazole drug, like any medication, can vary from person to person. Common side effects may include:
Headache
Diarrhea
Abdominal pain
Nausea
Vomiting
Gas
Constipation
Dry mouth
Dizziness
Fatigue
Less common but more serious side effects may include:
Severe stomach pain
Persistent nausea or vomiting
Difficulty swallowing
Severe diarrhea
Unexplained weight loss
Persistent cough or hoarseness
Signs of kidney problems (such as changes in the amount of urine)
Signs of liver problems (such as yellowing of the skin or eyes, dark urine, persistent nausea/vomiting, severe stomach/abdominal pain)
If you experience any severe side effects or signs of an allergic reaction (such as rash, itching/swelling, severe dizziness, trouble breathing), seek medical attention immediately. Always consult your healthcare provider for personalized advice regarding medication side effects.
Some advantages of dexlansoprazole drug
Dexlansoprazole is a proton pump inhibitor (PPI) used to treat conditions related to excessive stomach acid production. Some of its advantages include:
Effective Acid Reduction: Dexlansoprazole effectively inhibits the production of stomach acid, providing relief from symptoms of conditions like gastroesophageal reflux disease (GERD), erosive esophagitis, and gastric ulcers.
Long-Lasting Action: It has an extended-release formulation that allows for once-daily dosing, maintaining acid suppression over a prolonged period, which can improve patient compliance.
Fewer Drug Interactions: Compared to some other PPIs, dexlansoprazole may have fewer interactions with other medications, making it suitable for patients who require multiple drug therapies.
Convenience: Its once-daily dosing regimen offers convenience for patients, reducing the frequency of medication intake compared to some other PPIs that may require twice-daily dosing.
Symptom Relief: Dexlansoprazole effectively alleviates symptoms associated with conditions such as heartburn, acid reflux, and stomach ulcers, improving the quality of life for patients suffering from these ailments.
Healing Properties: It can help in the healing and prevention of damage to the esophagus caused by stomach acid, promoting the healing of erosive esophagitis and reducing the risk of its recurrence.
Variety of Dosage Strengths: Dexlansoprazole is available in different dosage strengths, allowing for personalized treatment based on the severity of the condition and individual patient needs.
As with any medication, it’s essential to consult with a healthcare professional to determine if dexlansoprazole is appropriate for your specific condition and medical history.
Some usage tips for dexlansoprazole drug
Here are some usage tips for dexlansoprazole:
Take it as Directed: Follow your healthcare provider’s instructions regarding dosage and timing. Typically, dexlansoprazole is taken once daily before a meal.
Consistency: Take dexlansoprazole at the same time each day to maintain consistent levels in your bloodstream.
Swallow Whole: Swallow the dexlansoprazole capsule whole. Do not crush, chew, or split the capsule, as it has an extended-release formulation designed for gradual release in the body.
Timing with Meals: Take dexlansoprazole before a meal, preferably in the morning. This helps optimize its effectiveness in reducing stomach acid production when it’s needed most.
Avoid Certain Foods and Beverages: Some foods and beverages can exacerbate stomach acid production and GERD symptoms. Avoid or limit consumption of spicy foods, acidic foods, caffeine, alcohol, and carbonated beverages.
Monitor Symptoms: Keep track of your symptoms and report any persistent or worsening symptoms to your healthcare provider. Dexlansoprazole should provide relief from heartburn, acid reflux, and other symptoms associated with excessive stomach acid production.
More tips
Duration of Use: Dexlansoprazole drug is typically prescribed for a specific duration, depending on the condition being treated. Do not exceed the prescribed duration without consulting your healthcare provider.
Medical Follow-up: Attend regular follow-up appointments with your healthcare provider to monitor your response to dexlansoprazole and assess the need for continued treatment.
Caution with Other Medications: Inform your healthcare provider about all medications, vitamins, and supplements you are taking, as dexlansoprazole may interact with certain drugs. This includes prescription medications, over-the-counter drugs, and herbal supplements.
Lifestyle Modifications: In addition to medication, lifestyle changes such as weight loss (if overweight), elevation of the head of the bed while sleeping, and avoiding lying down immediately after eating can help manage GERD symptoms more effectively.
Remember to consult your healthcare provider if you have any questions or concerns about the use of dexlansoprazole or if you experience any adverse effects.